Paper List
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Autonomous Agents Coordinating Distributed Discovery Through Emergent Artifact Exchange
This paper addresses the fundamental limitation of current AI-assisted scientific research by enabling truly autonomous, decentralized investigation w...
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D-MEM: Dopamine-Gated Agentic Memory via Reward Prediction Error Routing
This paper addresses the fundamental scalability bottleneck in LLM agentic memory systems: the O(N²) computational complexity and unbounded API token ...
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Countershading coloration in blue shark skin emerges from hierarchically organized and spatially tuned photonic architectures inside skin denticles
This paper solves the core problem of how blue sharks achieve their striking dorsoventral countershading camouflage, revealing that coloration origina...
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Human-like Object Grouping in Self-supervised Vision Transformers
This paper addresses the core challenge of quantifying how well self-supervised vision models capture human-like object grouping in natural scenes, br...
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Hierarchical pp-Adic Framework for Gene Regulatory Networks: Theory and Stability Analysis
This paper addresses the core challenge of mathematically capturing the inherent hierarchical organization and multi-scale stability of gene regulator...
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Towards unified brain-to-text decoding across speech production and perception
This paper addresses the core challenge of developing a unified brain-to-text decoding framework that works across both speech production and percepti...
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Dual-Laws Model for a theory of artificial consciousness
This paper addresses the core challenge of developing a comprehensive, testable theory of consciousness that bridges biological and artificial systems...
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Pulse desynchronization of neural populations by targeting the centroid of the limit cycle in phase space
This work addresses the core challenge of determining optimal pulse timing and intensity for desynchronizing pathological neural oscillations when the...
Scalable DNA Ternary Full Adder Enabled by a Competitive Blocking Circuit
Institute of Computational Science and Technology, Guangzhou University, China | School of Computer Science and Technology, Wuhan University of Science and Technology, China | School of Computer Science and Technology, Dalian University of Technology, China | School of Computing Science, Peking University, China
30秒速读
IN SHORT: This paper addresses the core bottleneck of carry information attenuation and limited computational scale in DNA binary adders by introducing a scalable ternary architecture.
核心创新
- Methodology Proposes a novel Competitive Blocking (CB) circuit that leverages differential reaction kinetics (k2 ≫ k1, k3) to dynamically select and block reaction pathways for precise carry information management.
- Methodology Introduces a ternary (base-3) adder architecture, moving beyond binary systems, which inherently reduces the frequency of carry propagation and increases single-bit information density.
- Methodology Implements a Dynamic Concentration Adjustment (CA) strategy, applying chemical equilibrium principles to optimize reactant ratios and signal transmission, enabling significant bit-width extension.
主要结论
- The CB circuit reliably performs ternary full-adder logic, with experimental validation showing successful 10-bit addition operations.
- The integrated CA strategy enables the adder to scale to 17-bit addition, representing a massive increase in computational scale.
- The architecture achieves a 'scale/strand' metric improvement of 2,405,552x compared to a recent state-of-the-art binary DNA adder capable of only 4 consecutive carries.
摘要: DNA adder circuits are programmable reaction networks that process DNA molecular inputs to compute a sum and serve as essential components for digital computation. Currently, DNA adders primarily focus on binary addition. While efforts extend the operational bit-width by minimizing the number of DNA strands and developing carry-transmission mechanisms, challenges such as the susceptibility of carrying information to attenuation and the limited expressive capacity of the binary system impose significant constraints on computational scale. This paper proposes a scalable ternary adder architecture by introducing an innovative competitive blocking (CB) circuit. The architecture employs a dual cooperative optimization strategy that significantly enhances single-bit computational capacity and incorporates a dynamic concentration adjustment (CA) to effectively broaden the computational bit-width. Consequently, a significant increase in molecular computing scale is achieved compared to previous binary adders. Biochemical experimental results indicate that the CB circuit effectively outputs the ternary full-adder bit and successfully performs 10-bit addition. Furthermore, by implementing the CA strategy, this adder can be further extended to support 17-bit addition. This research provides a novel methodological foundation for advancing DNA computing technologies and offers promising potential for scalable digital computing applications.