Paper List
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Discovery of a Hematopoietic Manifold in scGPT Yields a Method for Extracting Performant Algorithms from Biological Foundation Model Internals
This work addresses the core challenge of extracting reusable, interpretable, and high-performance biological algorithms from the opaque internal repr...
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MS2MetGAN: Latent-space adversarial training for metabolite–spectrum matching in MS/MS database search
This paper addresses the critical bottleneck in metabolite identification: the generation of high-quality negative training samples that are structura...
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Toward Robust, Reproducible, and Widely Accessible Intracranial Language Brain-Computer Interfaces: A Comprehensive Review of Neural Mechanisms, Hardware, Algorithms, Evaluation, Clinical Pathways and Future Directions
This review addresses the core challenge of fragmented and heterogeneous evidence that hinders the clinical translation of intracranial language BCIs,...
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Less Is More in Chemotherapy of Breast Cancer
通过纳入细胞周期时滞和竞争项，解决了现有肿瘤-免疫模型的过度简化问题，以定量比较化疗方案。
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Fold-CP: A Context Parallelism Framework for Biomolecular Modeling
This paper addresses the critical bottleneck of GPU memory limitations that restrict AlphaFold 3-like models to processing only a few thousand residue...
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Open Biomedical Knowledge Graphs at Scale: Construction, Federation, and AI Agent Access with Samyama Graph Database
This paper addresses the core pain point of fragmented biomedical data by constructing and federating large-scale, open knowledge graphs to enable sea...
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Predictive Analytics for Foot Ulcers Using Time-Series Temperature and Pressure Data
This paper addresses the critical need for continuous, real-time monitoring of diabetic foot health by developing an unsupervised anomaly detection fr...
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Hypothesis-Based Particle Detection for Accurate Nanoparticle Counting and Digital Diagnostics
This paper addresses the core challenge of achieving accurate, interpretable, and training-free nanoparticle counting in digital diagnostic assays, wh...
Dual-Laws Model for a theory of artificial consciousness
Department of mechano-informatics, The University of Tokyo, Japan
30秒速读
IN SHORT: This paper addresses the core challenge of developing a comprehensive, testable theory of consciousness that bridges biological and artificial systems, moving beyond narrow generative mechanisms to encompass functional aspects and causal efficacy.
核心创新
- Methodology Proposes seven fundamental questions (phenomena, self, causation, state, function, contents, universality) as a minimum necessary framework for evaluating consciousness theories, shifting focus from purely generative mechanisms to functional aspects.
- Theory Introduces the Dual-Laws Model (DLM) that formalizes consciousness through supervenience relationships with independent dynamics at two levels, enabling inter-level causation without relying on neural-specific implementations.
- Methodology Unifies the DLM with dual-process theories by mapping Type 1 processes to continuous feedback control at the base level and Type 2 processes to discrete algorithmic control at the supervenience level.
主要结论
- The DLM provides a formal framework where supervenient functions (X_i = b_i(x_i)) enable independent dynamics at two levels, allowing inter-level causation through negative feedback control mechanisms.
- Conscious systems require two unique capabilities: autonomy in goal construction and cognitive decoupling from external stimuli, distinguishing them from instruction-following machines.
- The theory rejects panpsychism and single-layer dynamical systems, proposing that consciousness emerges from dual-level feedback control where the supervenience level (corresponding to 'I') modifies index sequences that determine error functions.
摘要: Objectively verifying the generative mechanism of consciousness is extremely difficult because of its subjective nature. As long as theories of consciousness focus solely on its generative mechanism, developing a theory remains challenging. We believe that broadening the theoretical scope and enhancing theoretical unification are necessary to establish a theory of consciousness. This study proposes seven questions that theories of consciousness should address: phenomena, self, causation, state, function, contents, and universality. The questions were designed to examine the functional aspects of consciousness and its applicability to system design. Next, we will examine how our proposed Dual-Laws Model (DLM) can address these questions. Based on our theory, we anticipate two unique features of a conscious system: autonomy in constructing its own goals and cognitive decoupling from external stimuli. We contend that systems with these capabilities differ fundamentally from machines that merely follow human instructions. This makes a design theory that enables high moral behavior indispensable.