Paper List
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A Unified Variational Principle for Branching Transport Networks: Wave Impedance, Viscous Flow, and Tissue Metabolism
This paper solves the core problem of predicting the empirically observed branching exponent (α≈2.7) in mammalian arterial trees, which neither Murray...
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Household Bubbling Strategies for Epidemic Control and Social Connectivity
This paper addresses the core challenge of designing household merging (social bubble) strategies that effectively control epidemic risk while maximiz...
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Empowering Chemical Structures with Biological Insights for Scalable Phenotypic Virtual Screening
This paper addresses the core challenge of bridging the gap between scalable chemical structure screening and biologically informative but resource-in...
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A mechanical bifurcation constrains the evolution of cell sheet folding in the family Volvocaceae
This paper addresses the core problem of why there is an evolutionary gap in species with intermediate cell numbers (e.g., 256 cells) in Volvocaceae, ...
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Bayesian Inference in Epidemic Modelling: A Beginner’s Guide Illustrated with the SIR Model
This guide addresses the core challenge of estimating uncertain epidemiological parameters (like transmission and recovery rates) from noisy, real-wor...
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Geometric framework for biological evolution
This paper addresses the fundamental challenge of developing a coordinate-independent, geometric description of evolutionary dynamics that bridges gen...
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A multiscale discrete-to-continuum framework for structured population models
This paper addresses the core challenge of systematically deriving uniformly valid continuum approximations from discrete structured population models...
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Whole slide and microscopy image analysis with QuPath and OMERO
使QuPath能够直接分析存储在OMERO服务器中的图像而无需下载整个数据集,克服了大规模研究的本地存储限制。
PesTwin: a biology-informed Digital Twin for enabling precision farming
Multiple institutions (likely Italian research institutes and universities)
30秒速读
IN SHORT: This paper addresses the critical bottleneck in precision agriculture: the inability to accurately forecast pest outbreaks in real-time, leading to suboptimal pesticide applications and significant crop losses.
核心创新
- Methodology Developed a modular, biology-informed Digital Twin framework using Agent-Based Modeling that integrates heterogeneous data sources (lab biodata, weather stations, GIS) for pest forecasting
- Methodology Implemented GPU-accelerated ABM using FLAMEGPU library, enabling simulation of up to 80 million concurrent agents for realistic field-scale scenarios
- Biology Applied the framework to Drosophila suzukii (Spotted Wing Drosophila) with comprehensive lab protocols for parameter calibration, including temperature-dependent development using modified-Brierè functions
主要结论
- The PesTwin framework successfully simulated SWD population growth in cage experiments, capturing biological variability across three replicates with stochastic modeling matching experimental data.
- Field simulations showed qualitative agreement with trapping data, demonstrating capability to model pest dispersal, host interactions, and temperature-dependent lifecycle dynamics in realistic scenarios.
- Simulation of Sterile Insect Technique (SIT) control strategy demonstrated potential to reduce pest populations by more than half (50%+ reduction) when implementing weekly releases during crop ripening season.
摘要: In a context of growing agricultural demand and new challenges related to food security and accessibility, boosting agricultural productivity is more important than ever. Reducing the damage caused by invasive insect species is a crucial lever to achieve this objective. In support of these challenges, and in line with the principles of precision agriculture and Integrated Pest Management (IPM), an innovative simulation framework is presented, aiming to become the Digital Twin of a pest invasion. Through a flexible rule-based approach of the Agent-Based Modeling (ABM) paradigm, the framework supports the fine-tuning of the main ecological interactions of the pest with its crop host and the environment. Forecasting insect infestation in realistic scenarios, considering both spatial and temporal dimensions, is made possible by integrating heterogeneous data sources: pest biodata collected in the laboratory, environmental data from weather stations, and GIS data of a real crop field. In this study, an application to the global pest of soft fruit, the invasive fruit fly Drosophila suzukii, also known as Spotted Wing Drosophila (SWD), is presented.